Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Mouse CD22 mAb
Enables CD4 receptor binding activity protein phosphatase binding activity and sialic acid binding activity Involved in several processes including negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production and regulation of B cell proliferation Located in external side of plasma membrane and neuronal cell body membrane Is integral component of plasma membrane Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Orthologous to human CD22 (CD22 molecule)
ABclonal Technology 647 Rabbit anti-Human CD34
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Mouse CD62E mAb
Predicted to enable several functions including oligosaccharide binding activity phospholipase binding activity and sialic acid binding activity Involved in positive regulation of leukocyte tethering or rolling Acts upstream of or within positive regulation of leukocyte migration Predicted to be located in several cellular components including caveola clathrin-coated pit and perinuclear region of cytoplasm Predicted to be integral component of plasma membrane Predicted to be active in external side of plasma membrane and extracellular space Is expressed in several structures including adrenal gland genitourinary system incisor integumental system and limb segment Human ortholog(s) of this gene implicated in IgA glomerulonephritis brain ischemia cerebrovascular disease and coronary artery disease Orthologous to human SELE (selectin E)
ABclonal Technology 647 Rabbit anti-Human CD34
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 647 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 594 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 647 Rabbit anti-Human CD300a
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Mouse CD40 mAb
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
ABclonal Technology PE Rabbit anti-Mouse/Rat CD27
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process Involved in negative regulation of apoptotic process and positive regulation of JNK cascade Acts upstream of or within negative regulation of T cell apoptotic process Located in external side of plasma membrane Is expressed in several structures including femur hemolymphoid system intestine pituitary gland and reproductive system Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2 Orthologous to human CD27 (CD27 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD68 mAb
Involved in several processes including cellular response to lipopolysaccharide cellular response to oxidised low-density lipoprotein particle stimulus and negative regulation of dendritic cell antigen processing and presentation Acts upstream of or within aging and cellular response to organic substance Located in lysosome and plasma membrane Is expressed in several structures including central nervous system embryo mesenchyme heart blood vessel liver and spleen Orthologous to human CD68 (CD68 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD68 mAb
Involved in several processes including cellular response to lipopolysaccharide cellular response to oxidised low-density lipoprotein particle stimulus and negative regulation of dendritic cell antigen processing and presentation Acts upstream of or within aging and cellular response to organic substance Located in lysosome and plasma membrane Is expressed in several structures including central nervous system embryo mesenchyme heart blood vessel liver and spleen Orthologous to human CD68 (CD68 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD68 mAb
Involved in several processes including cellular response to lipopolysaccharide cellular response to oxidised low-density lipoprotein particle stimulus and negative regulation of dendritic cell antigen processing and presentation Acts upstream of or within aging and cellular response to organic substance Located in lysosome and plasma membrane Is expressed in several structures including central nervous system embryo mesenchyme heart blood vessel liver and spleen Orthologous to human CD68 (CD68 molecule)
ABclonal Technology KPNA6 Rabbit mAb
Nucleocytoplasmic transport a signal- and energy-dependent process takes place through nuclear pore complexes embedded in the nuclear envelope The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor a heterodimer of importin alpha and beta subunits also known as karyopherins Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex In the presence of nucleoside triphosphates and the small GTP binding protein Ran the complex moves into the nuclear pore complex and the importin subunits dissociate Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore The protein encoded by this gene is a member of the importin alpha family
ABclonal Technology ABflo 488 Rabbit anti- CD40
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD25 mAb
Enables interleukin-2 binding activity and interleukin-2 receptor activity Acts upstream of or within several processes including Notch signaling pathway activation-induced cell death of T cells and regulation of T cell proliferation Located in external side of plasma membrane Is expressed in bone marrow Used to study Sjogren s syndrome and inflammatory bowel disease Human ortholog(s) of this gene implicated in immunodeficiency 41 lymphopenia multiple sclerosis type 1 diabetes mellitus and type 1 diabetes mellitus 10 Orthologous to human IL2RA (interleukin 2 receptor subunit alpha)